Protein Modification Reagents
Medchemexpress LLC Dspe-peg-sh | 99.4% | 2000 (average) | (C2H4O)nC45H87N2O10PS | 25 MG
DSPE-PEG-SH is a thiolated pegylated phospholipid (average MW 2000) that provides a terminal -SH for covalent surface modification of lipid assemblies. Its amphipathic DSPE-PEG structure enables incorporation into liposomes and lipid nanoparticles for ligand attachment, stabilization, and targeted delivery via formation of stable thioether bonds with maleimide-functionalized molecules.
- Provides a terminal thiol for covalent conjugation.
- Incorporates into lipid bilayers for surface functionalization.
- Enables stable thioether linkage with maleimide reagents.
- Suitable for liposome and lipid nanoparticle formulations.
- Facilitates targeted delivery via ligand attachment.
- Reported high purity supports reproducible formulation.
- Soluble in water and DMSO with warming and sonication.
![Medchemexpress LLC 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[poly(ethylene glycol)-maleimide] ammonium | 474922-22-0 | >95.0% | 3,400 Da | (C2H4O)nC51H92N3O13P.H3N | 250 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000281718.png-250.jpg)
Medchemexpress LLC 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[poly(ethylene glycol)-maleimide] ammonium | 474922-22-0 | >95.0% | 3,400 Da | (C2H4O)nC51H92N3O13P.H3N | 250 MG
DSPE-PEG-Maleimide (MW 3400) ammonium is a PEGylated phospholipid bearing a terminal maleimide group and supplied as the ammonium salt. It is used to introduce thiol-reactive functionality into liposomes, micelles, and other nanostructured lipid carriers for conjugation of peptides, proteins, and thiolated ligands in drug delivery and nanomedicine research.
- Provides a terminal maleimide for selective conjugation to thiol groups.
- PEG spacer (MW ~3,400) improves steric stabilization and circulation time.
- DSPE lipid anchor enables stable incorporation into lipid bilayers and micelles.
- Ammonium salt form aids solubility and handling in formulation workflows.
- Typical purity ≥95% suitable for research applications; verify COA for critical uses.
eMolecules 1008402-47-8 | Bis-Mal-PEG3 | Broadpharm | MFCD22683311 | 494.501 | C22H30N4O9 | 98.000 | O=C(CCN1C(=O)C=CC1=O)NCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O | 250mg | 200183412
Bis-Mal-PEG3 | Broadpharm | 1008402-47-8 | MFCD22683311 | 494.501 | C22H30N4O9 | 98.000 | O=C(CCN1C(=O)C=CC1=O)NCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O | 250mg | 200183412
eMolecules 2698339-32-9 | Methyltetrazine-amido-bis-(carboxyethoxymethyl)-methane | Broadpharm447.448 | C20H25N5O7 | 95.000 | Cc1nnc(nn1)-c1ccc(CC(=O)NC(COCCC(O)=O)COCCC(O)=O)cc1 | 50mg | 649280885
Methyltetrazine-amido-bis-(carboxyethoxymethyl)-methane | Broadpharm | 2698339-32-9447.448 | C20H25N5O7 | 95.000 | Cc1nnc(nn1)-c1ccc(CC(=O)NC(COCCC(O)=O)COCCC(O)=O)cc1 | 50mg | 649280885
eMolecules 2170240-96-5 | Medchem Express | Azido-PEG4-hydrazide | 50mg | 600899956 | HY-140814 | 305.335 | C11H23N5O5
Ambeed | 3-Bromo-4-(4455-tetramethyl-132-dioxaborolan-2-yl)pyridine | 250mg | 521437554 | A341459 | 458532-92-8 | MFCD06798250 | 283.960 | C11H15BBrNO2
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Cayman Chemical dPE-PEG 2000 MaleImIde 5mg
A metabolite of linoleic acid increases transactivation of PPARa and PPARY in reporter assays using mouse aortic endothelial cells at 68 UM induces chemotaxis of primary human monocytes at 10 UM has been found in oxLDL
Medchemexpress LLC Nh2-C5-PEG4-N3-L-lysine-PEG3-N3 | 99.4% | 619.71 g/mol | C25H49N9O9 | 10 MG
NH2-C5-PEG4-N3-L-Lysine-PEG3-N3 is a cleavable 7-unit polyethylene glycol (PEG) linker containing an azide and a free amine, designed for antibody-drug conjugate assembly and click-chemistry bioconjugation. It is water-soluble, compatible with copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC), and is supplied for small-scale research use.
- Cleavable 7-unit PEG linker with azide and amine functional groups.
- High purity suitable for conjugation chemistries.
- Water soluble at high concentration (≥100 mg/mL) for concentrated reactions.
- Compatible with CuAAC and SPAAC click chemistry methods.
- Available in small mg quantities for research and development.
- Storage recommendations: powder -20°C; in solvent -80°C (6 months) or -20°C (1 month).
eMolecules 159156-95-3 | N-Boc-PEG24-alcohol | Broadpharm | MFCD29052164 | 1174.420 | C53H107NO26 | 98.000 | CC(C)(C)OC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO | 1g | 296213189
N-Boc-PEG24-alcohol | Broadpharm | 159156-95-3 | MFCD29052164 | 1174.420 | C53H107NO26 | 98.000 | CC(C)(C)OC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO | 1g | 296213189
![eMolecules 2107272-96-6 | N-(m-PEG4)-N'-(amino-PEG3)-Cy5, TFA salt | Broadpharm870.450 | C44H63ClF3N3O9 | 97.000 | [Cl-].OC(=O)C(F)(F)F.COCCOCCOCCOCCN1\C(=C\C=C\C=C\C2=[N+](CCOCCOCCOCCN)c3ccccc3C2(C)C)C(C)(C)c2ccccc12 | 10mg | 298819349](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502203362.JPG-250.jpg)
eMolecules 2107272-96-6 | N-(m-PEG4)-N'-(amino-PEG3)-Cy5, TFA salt | Broadpharm870.450 | C44H63ClF3N3O9 | 97.000 | [Cl-].OC(=O)C(F)(F)F.COCCOCCOCCOCCN1\C(=C\C=C\C=C\C2=[N+](CCOCCOCCOCCN)c3ccccc3C2(C)C)C(C)(C)c2ccccc12 | 10mg | 298819349
N-(m-PEG4)-N'-(amino-PEG3)-Cy5, TFA salt | Broadpharm | 2107272-96-6870.450 | C44H63ClF3N3O9 | 97.000 | [Cl-].OC(=O)C(F)(F)F.COCCOCCOCCOCCN1\C(=C\C=C\C=C\C2=[N+](CCOCCOCCOCCN)c3ccccc3C2(C)C)C(C)(C)c2ccccc12 | 10mg | 298819349
Research Products International Corp PEG 8000, 15 KG
Ultrapure white crystals for molecular biology applications such as precipitation of DNA, nucleic acids, hybridization and fusion of mammalian cells.Melting Point: 55°-60°C
![eMolecules 113072-75-6 | Biotin-PEG5-amine | Broadpharm | MFCD22574819 | 506.660 | C22H42N4O7S | 98.000 | NCCOCCOCCOCCOCCOCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 1g | 309209149](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502202951.JPG-250.jpg)
eMolecules 113072-75-6 | Biotin-PEG5-amine | Broadpharm | MFCD22574819 | 506.660 | C22H42N4O7S | 98.000 | NCCOCCOCCOCCOCCOCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 1g | 309209149
Biotin-PEG5-amine | Broadpharm | 113072-75-6 | MFCD22574819 | 506.660 | C22H42N4O7S | 98.000 | NCCOCCOCCOCCOCCOCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 1g | 309209149
eMolecules 1346502-15-5 | Bromo-PEG3-CH2CO2H | Broadpharm | MFCD30468772 | 271.107 | C8H15BrO5 | 98.000 | OC(=O)COCCOCCOCCBr | 1g | 343283604
Bromo-PEG3-CH2CO2H | Broadpharm | 1346502-15-5 | MFCD30468772 | 271.107 | C8H15BrO5 | 98.000 | OC(=O)COCCOCCOCCBr | 1g | 343283604
Medchemexpress LLC Biotin-PEG4-hydrazide | 756525-97-0 | 99.9% | C21H39N5O7S | 100 MG
Biotin-PEG4-hydrazide is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Biotin-labeled
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Enables selective degradation of target proteins via the intracellular ubiquitin-proteasome system
Medchemexpress LLC 4-Arm PEG-SCM MW 10 1g
4-Arm PEG-SCM (MW 10000) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery[1]